Tramadol: A Medical Guide

History and Emergence:

• First discovered in Germany in the 1970s by Grunthal GmbH, Tramadol is a synthetic opioid pain reliever or analgesic.
• It was first called Tramal and gained popularity for its fast-acting pain-reducing mechanism.
• By the ’90s came, it got approved for use in many countries.

Mechanism:

Tramadol is an opioid pain medication and also an antidepressant medication. It is effective in treating moderate to severe pain with its dual mechanism of inhibiting the reuptake of norepinephrine and serotonin and binding mu-opioid receptors in the brain and spinal cord. It alters the response to pain and provides relief.

Dosage Instructions:

• Dosage should be strictly as per your doctor’s advice to avoid any risks.
• Typically, the dosage varies from 50-100mg, every 4-6 hours.
• The pill needs to be taken with water.

Indications and Contradictions:

Indications:

• Moderate to severe pain
• Chronic mild pain

Contradictions:

• Allergic to Tramadol
• Alcohol Intoxication
• Troubled breathing or asthma

Side Effects:

Common Side Effects:

• Nausea
• Vomiting
• Headache
• Constipation
• Fatigue

Severe Side Effects:

• Serotonin Syndrome
• Respiratory Syndrome
• Allergic Reaction

Note: if you experience any severe side effects, seek medical help immediately.

 Precautions and Storage Information:

• Consult with your doctor if you’re pregnant or breastfeeding
• The drug can cause cognitive imbalance, so it is advised to avoid driving or operating heavy machinery
• Inform your healthcare provider regarding other medications you’re currently taking to avoid drug interactions.
• Store in a cool, dry place away from direct heat or light.
• Keep out of reach of children and pets.

Conclusion

Tramadol is an effective drug in the world of pain management but like any other medication, it should be administered strictly under medical supervision to avoid any potential risks and navigate through the procedure safely.